Step 1: synthesis of benzoin this reaction is a classic--the conversion of two molecules of an aldehyde to an alpha-hydroxy ketone the reaction is known as a benzoin condensation (condensation because two molecules become condensed to one molecule) this reaction, which requires a catalyst, if often performed with cyanide ion. What is the mechanism for synthesis of tetraphenylcyclopentadienone organic chemistry welcome to organic chemistry definition of 'chemistry' and 'organic' 1 answer truong-son n jan 16, 2016 looks like this can be formed via two aldol condensations nice let's see alright, let's start with these two compounds, then:.
Thiamine is heat sensitive so the addition of 5 m naoh needs to be added slowly (3 to 5 min) to the thiamine hydrochloride in an ice bath with constant swirling and maintain the temperature below. Multistep synthesis of 2,3,4,5-tetraphenylcyclopentadienone the multistep synthesis of 2,3,4,5-tetraphenylcyclopentadienone is divided into three consecutive steps.
Each of the reactions was performed in the conditions they were in order to maximize the yields and so that the reactions would proceed as fully as would be possible because benzaldehyde has no alpha hydrogens off of its carbonyl group, it cannot undergo an aldol condensation reaction however, the benzoin condensation, which is a reaction that is unique to benzaldehyde, will occur when mixed. Multistep synthesis started first with benzoin then from benzoin, different steps were performed in order to form 2,3,4,5-tetraphenylcyclopentadienone it is a very tough experiment and you might get very little yield on some of the intermediate products. The aim of this experiment was to perform a multistep synthesis to form tetraphenylcyclopentadienone the first step of the reactions was to synthesize benzoin from the condensation of benzaldehyde a yield of 2891% benzoin was obtained.
Multistep synthesis of tetraphenylcyclopentadienone author: instructor: date work performed: 10182012--10252012 date work submitted: 11012012 abstract: the aim of this experiment was to perform a multistep synthesis to form tetraphenylcyclopentadienone the first step of the reactions was to synthesize benzoin from the condensation of benzaldehyde. Multistep synthesis of tetrapentadienone author: nikhita pakki instructor: bobbi anglin section: 5 date lab performed: october 16, and 23, 2012 date report submitted: november 30,2012 abstract in this experiment, we synthesized tetraphenylcyclopentadienone, to do this, we performed three steps. Step 1: synthesis of benzoin this reaction is a classic--the conversion of two molecules of an aldehyde to an alpha-hydroxy ketone the reaction is known as a benzoin condensation (condensation because two molecules become condensed to one molecule.
The last step of the synthesis was a double aldol condensation reaction to form tetraphenylcyclopentadienone this reaction had a yield of 7656% and a melting point of 222o-225o c the ir spectra revealed a ketone carbonyl peak at 1700 cm-1. You will have an opportunity to do a multistep synthesis starting with inexpensive, readily available benzaldehyde the sequence you will attempt is first the conversion of benzaldehyde to benzoin using the vitamin, thiamin, as a catalyst into a 10 ml beaker, place 39 mg of tetraphenylcyclopentadienone (010 mmol), 3 drops of dimethyl. Synthesis of tetraphenylcyclopentadienone in the last part of the work up, tetraphenylcyclopentadienone was synthesized through a double aldol condensation reaction a water bath was first prepared and heated to 100o c. Multistep synthesis when synthesizing complex organic molecules, it is common to have at least a (1,3-diphenyl-2-propanone) to produce tetraphenylcyclopentadienone an alternative third step is the reduction of benzil to dihydrobenzoin with a reducing agent, sodium.
View lab report - multistep synthesis of tetraphenylcyclopentadienone from chem 243b at university of arizona multistep synthesis of tetraphenylcyclopentadienone instructor: xin wu chem 243b date. Multistep synthesis of tetraphenylcyclopentadienone in this laboratory experiment a synthesis was performed through several separate steps the purpose of the experiment was to synthesize tetraphenylcyclopentadienone from benzaldehyde and to run reactions on carbonyl containing compounds.
The last step is a diels alder reaction between diphenylacetylene (v-11) and tetraphenylcyclopentadienone (v-07) with loss of co to give hexaphenylbenzene (v-12)2) synthetic procedures 21 synthesis of benzoin (v-03)vitamin b.